Lopo Homem (16th century) was a Portuguese cartographer and cosmographer.
His earliest known work is a world map, discovered in London in 1930. In Florence there is another world map dated 1554, and Lisbon's National Library has also a navigation chart (which before 1910 was in the Palácio das Necessidades, having belonged to Charles I of Portugal). Scholar Armando Cortesão's "Cartography and Portuguese cartographers in the fifteenth and sixteenth" includes an extensive section devoted to Lopo Homem.